New Dietary Ingredient helps to hydrate skin, fight against signs of aging,
and leave skin soft and supple.
Lipowheat® achieved NDI (New Dietary Ingredient) status after the recent application with the FDA.
Lipowheat restores skin barrier function ensuring a healthy hydration mechanism. Our skin is the largest and arguably the most important organ of the body. The stratum corneum is the corneal layer composed of keratinized, fused, flat cells that are bound together by lipids. Among these lipids, cholesterol, free fatty acids and ceramides (sphingolipids) each found in intercellular cement and squalene found in the hydrophilic film, play a major role in the skin’s integrity,health and protective properties. The ceramides of Lipowheat protect the “treasure cells” of the skin – the fibroblasts.
The composition of the stratum corneum changes with age and with the seasons. Scientists have linked decreases in skin lipid concentration to winter weather and the aging process. These modifications lead to dry skin and to all the commonly observed associated signs such as squames, itching, roughness.
In vitro tests, topical applications, clinical studies, oral ingestion
Ceramides are widely studied for their dramatic role in skin hydration (1,2,3).
Lipowheat efficacy has been shown through three clinical studies on a total of 135 volunteers (4,5).
- Castiel Higounenc - “Stratum corneum lipids: specificity, role, deficiencies and modulation”, OCL, 2004, vol. 11 n. 6.
- Imokawa G - “Importance of intracellular lipids in water retention properties of stratum corneum: induction and recovery study of surfactant dry skin” Arch Dermatol Res., 281:45:51.
- Tsuji K - “Dietary glucosylceramide improves skin barrier function in hairless mice”, 2006, J Dermatol Sci, 44: 101-7.
- Djedour A - “A very promising new glucolipidic surfactant: Lipowheat, International Journal of Cosmetic Science, 2005, 27 301-8.
- Boisnic S - “Intèrêt clinique d’un ingrédient alimentaire à visée hydrantante: Lipowheat Edudie randomisée en double avegule versus placebo.” J. Med Esth. Et Chir. Derm., 2007, vol 34, 136:239-242.