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Clinical Research

New Clinical Study on Zynamite® S shows enhanced mood and reduced fatigue in 30 minutes along with faster information processing and improved cognitive performance

Study Highlights

New Study Shows Broad-Ranging Benefits from a Single Dose

In the new clinical study, 88 healthy university students were given a single dose of 100 mg Zynamite S or a matching placebo and then assessed three times over a 5-hour period. The study used a randomized, double-blind, placebo-controlled crossover design with a 7-day washout between testing conditions. Assessments were performed at baseline, 30 minutes, 3 hours, and 5 hours.

Participants completed two Trail Making Tests for cognitive speed and mental flexibility. A Stroop Color and Word Test assessed cognitive flexibility and inhibitory control. A Digit Substitution Test was used to evaluate attention, working memory, and processing speed. Finally, a Profile of Mood States Test (POMS) assessed mood, including total mood disturbances, tension, and depression.

Compared to placebo, subjects taking Zynamite S experienced:

  • Improved mood and reduced tension starting at 30 minutes, with a 24.1% improvement in 5 hours
  • Reduced fatigue in 30 minutes, with a 26% reduction in 5 hours
  • Improved attention and working memory by 17% at 5 hours with significant differences vs. placebo at 3 hours
  • An improvement of 25.4 in processing speed
  • A greater than 21% improvement in the ability to handle complex tasks
  • Improved selective attention and inhibitory control. These core executive functions help manage and control thoughts and actions and handle cognitive interference while processing multiple pieces of information simultaneously.

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