Morristown, NJ 29 April 2024 – PLT Health Solutions, Inc. announced that it has received a license from the Natural and Non-Prescription Health Products Directorate (NNHPD) of Health Canada to market its ingredient Nutricog® Cognitive Performance Complex to support cognitive health in Canada. Nutricog is a patented combination of Haritaki (Terminalia chebula) and Boswellia (Boswellia serrata) — standardized to gallic acid, ellagic acid and amyrins. In a randomized, double-blind, placebo-controlled clinical trial, users of Nutricog demonstrated significant improvements compared to placebo across multiple cognitive domains, including learning, memory, sustained attention, working memory and executive function, where increases in cognitive speed were seen concurrently with improvements in accuracy while multitasking.

The list of claims approved by Health Canada for Nutricog include:

• Helps to support cognitive health and/or brain function.
• Helps to support memory.
• Helps to support brain function
• Helps to support working memory and immediate recall
• Helps to support cognitive health and/or brain function.
• Helps to support (working) memory and immediate recall.
• Helps support cognitive function such as (selective) attention
• Helps support cognitive function in older people
• Helps to support verbal and visual memory.
• Helps to support learning ability.
• Helps to support selective attention
• Helps to support working memory
• Helps with sleep quality, over time

According to Seth Flowerman, President and CEO of PLT Health Solutions, the granting of an NHP license for Nutricog by Health Canada is significant for what it says about the science that supports Nutricog. “The broad range of cognitive performance benefits demonstrated in our clinical study make it ideal to support memory products, focus and attention products, general brain products and more. Health Canada has a high bar for clinically supported health claims, and we are proud of the quality of science supporting this innovative and breakthrough ingredient,” he added.

Studies demonstrate broad-ranging cognitive support

A randomized, double-blind, placebo-controlled clinical trial assessed Nutricog for its ability to impact learning and memory, including attention, working memory, and decision-making. 100 healthy male and female subjects, aged 40-65 years, were provided 120 days of daily Nutricog or placebo and assessed for performance improvements on the Rey Auditory Verbal Learning Test (RAVLT) and the Cambridge Neuropsychological Test Automated Battery (CANTAB), both well-established and validated tools used to evaluate learning, memory, and other aspects of cognitive performance. Other measures included the Athens Insomnia Scale and biomarker testing for Brain-derived Neurotrophic Factor (BDNF).

.Improvements in cognitive performance reported out from the study included:

• A 1.4x improvement in Immediate Recall*^
• A 2.3x improvement in Delayed Recall*^
• A 1.6x improvement in Overall Learning*^
• A 2.7x improvement in Learning Rate*^
• A 11.5x improvement in Focus*^
• A 2.1x improvement in Recognition Index*^
• A 2x improvement in BDNF*^

^ These outcomes were statistically significant compared to placebo in the clinical study

According to Jeremy Appleton, ND, Director of Medical and Scientific Affairs PLT Health Solutions, the broad range of benefits seen with the Nutricog clinical trial suggests a wide range of products into which it can be formulated. “The power of these clinical results is not just that Nutricog showed significance in such a broad array of areas, but the amount of change versus placebo that was demonstrated,” he said. “The market size and potential for knowledge workers alone—that includes over 100 million people— speaks to huge number of people who can benefit from this ingredient,” he added.

People of all age groups are tuning into the benefits of improved cognitive health and performance The cognitive health supplement market in the United States alone is expected to grow at a compound annual growth rate (CAGR) of 13.3% from 2023 to 2033, reaching a valuation of US$16.8 billion by 2033

Learn more about this ingredient

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE

Morristown, NJ 26 March 2024 – PLT Health Solutions, Inc. announced BioTRUST Nutrition® LLC, a leading eCommerce-based nutrition brand with a portfolio of high-quality, science-backed products focused on healthy aging and improving healthspan, has introduced a new product targeted at providing brain longevity and cognitive support called Eternal Mind®. The new product features PLT’s Nutricog® Cognitive Performance Complex, an ingredient that has been clinically demonstrated to provide significant improvements across multiple cognitive domains, including learning, memory, attention, focus, and executive function, where increases in cognitive speed were seen concurrently with improvements in accuracy while multitasking. In addition, clinical science showed that Nutricog doubled levels brain-derived neurotrophic factor (BDNF), a neuroprotein involved in the brain’s ability to adapt to new information.

Eternal Mind also features VitaCholine® and phosphatidylserine, both of which support healthy levels of critical neurochemicals involved in cognitive function, healthy memory, and long-term mental fitness; and Vitamins B6 and B12, two brain vitamins that support brain energy production, neurotransmitter synthesis, and homocysteine detoxification. Eternal Mind is available direct-to-consumer from the BioTRUST Nutrition website (www.biotrust.com) and via Amazon.

According to Chris Marschall, CEO, for Wellbeam Consumer Health, owner of BioTRUST Nutrition, the addition of Nutricog to this formulation allows the company to offer consumers a premium cognitive support capsule that delivers tangible results. “Brain and cognitive health are a significant concern for many Americans, especially as we age. However, navigating the cognitive supplement market can be challenging due to the prevalence of expensive products with ambiguous ‘proprietary blends’ and vague claims,” Chris Marschall said. “With Eternal Mind, we’re excited to offer a solution that stands out from the crowd. Our formulation features science-backed ingredients, including the latest double-blind clinical research on Nutricog, which demonstrated tangible improvements in vital cognitive functions such as memory, focus, concentration, and learning,” Chris explained.

Studies demonstrate broad-ranging cognitive support

Nutricog is a patented combination of Haritaki (Terminalia chebula) and Boswellia (Boswellia serrata), standardized to gallic acid, ellagic acid, and amyrins. According to BioTRUST®, Eternal Mind is backed by the latest science in brain health. Nutricog was shown to double the levels of BDNF in study subjects, supporting neuroplasticity, growth of new brain cells, and supporting formation of synaptic communication points.* Clinical results of the most recent study indicate support for everyday cognitive needs:

• Improved memory, focus, decision-making, and concentration*
• Improved recall speed by 130% – to help you effortlessly remember names and dates*
• Elevated focus up to 11.5x – to avoid distraction and maintain mental agility*
• More than doubling recognition memory – to help recognize names, facts, and places*
• Improved verbal and visual memory – to help you make fewer mistakes in recalling and processing information*
• Improved speed and accuracy of memory –so conversations can flow effortlessly*
• Improved cognitive processing speed – to help prevent embarrassing delays *
• Improved learning ability and learning rate – to make picking up new hobbies and technology more a breeze*

According to Steve Fink, Vice President of Marketing for PLT Health Solutions, BioTRUST Nutrition’s Eternal Mind sets new standards for cognitive support in an increasingly confusing marketplace. “Cognitive performance and long-term brain health are issues at the forefront of people’s minds these days. PLT Health Solutions is excited to work with BioTRUST on developing this product and we look forward to Eternal Mind bringing the benefits of Nutricog to many, many people,” he said

Eternal Mind is BioTRUST’s  second brain health product. An existing product, Brain Bright®, is formulated to deliver a same-day mental boost, emphasizing fast-acting results for more acute short-term benefits.

For more information on Eternal Mind, visit: www.biotrust.com

For more information on Nutricog, visit: www.plthealth.com/nutricog

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

About BioTRUST Nutrition

Founded in 2011, BioTRUST Nutrition is a leading eCommerce nutrition and supplement brand focused on promoting healthy aging. BioTRUST redefines healthy aging as enriching life’s quality, not just extending its duration. Committed to transparency and quality, BioTRUST offers a portfolio of meticulously crafted, naturally honest, science-backed products. These formulations are free from artificial colors, flavors, or sweeteners and are made with pasture-raised, hormone-free, and antibiotic-free ingredients. Beyond products, BioTRUST’s commitment extends to comprehensive educational resources, personalized guidance from expert coaches, and a thriving online community, empowering customers to lead healthier, more vibrant lives. BioTRUST is a Wellbeam Consumer Health brand and is available on the company’s website BioTRUST.com and on Amazon.