Featured News

Slendacor® Weight Management Complex Granted Patent for Research on Thermogenic Benefits

January 8, 2024
Slendacor® Weight Management Complex Granted Patent for Research on Thermogenic Benefits

Morristown, NJ 9 January 2024 – PLT Health Solutions, Inc. announced that Slendacor® Weight Management Complex has added to its intellectual property portfolio with a recently granted patent related to new clinical work that studied mechanisms of action behind its weight loss and body shaping benefits, and which demonstrated thermogenic benefits. The invention cited in the patent relates to Slendacor’s ability to increase lean body mass and accelerate the conversion of white adipose tissue to the more metabolically active brown or ‘beige’ adipose tissue. The Japanese patent was part of a global patent initiative by PLT and innovation partner Laila Nutraceuticals and is the first country patent granted as part of a PCT filing across multiple markets. Slendacor is also marketed as Slimvance® in select markets.

According to Seth Flowerman, President & CEO of PLT Health Solutions, the pursuit of intellectual property on the company’s proprietary branded ingredients is in line with its mission to deliver higher levels of value to the innovative consumer product brands PLT works with. “Part of delivering best-in-class ingredient solution is the ability to develop truly novel inventions backed by intellectual property on the innovation and supported by high quality clinical science,” he said. “We are pleased that the Japanese patent office has chosen to recognize the quality and innovative findings of the clinical science surrounding Slendacor. Our customers can be confident of the groundbreaking benefits and efficacy they can offer consumers with Slendacor,” he added.

Investing in on-going scientific support

Slendacor is a multi-patented combination of three standardized extracts of well-known spices: turmeric (Curcuma longa), drumstick leaves (Moringa oleifera), and curry leaves (Murraya koenigii). It has been studied in three human clinical trials to date and multiple pre-clinical studies.

A 2018 16-week double-blind, placebo-controlled study of Slendacor set new standards for communicating efficacy to consumers and regulatory agencies in the weight management category – because of its size, its length, its use of healthy, non-obese men and women, its design and execution. Consistent body weight reductions were observed throughout the 16-week trial – starting with statistically significant weight loss at two weeks. Participants averaged a total weight loss of nearly twelve pounds by the end of the study. The subjects taking Slendacor lost two inches in waist circumference and had no reduction in lean body mass.1

Two recent pre-clinical studies on energy expenditure illustrate a new mechanism of action in which Slendacor drives the increased expression of UCP-1 in white adipose tissue, similar to what occurs in more metabolically active brown adipose tissue.2,3 Most body fat is white adipose tissue, which functions as fat storage, however, brown adipose tissue can increase energy expenditure due to its greater concentration of mitochondria specialized for thermogenesis. Brown or ‘brown-like’ (beige) fat cells correlate with leanness in humans.

A recently completed human clinical trial (abstract published)4 was undertaken to further understand the thermogenic effects of Slendacor in human subjects. In this study, effects of a single daily dose of Slendacor on resting metabolic rate were evaluated using indirect calorimetry. Participants using Slendacor showed up to a 15.2% increase in resting energy expenditure (REE) on Day 7. Calorie burning increased significantly compared to baseline starting at 1 hour after intake on Day 1 of the study. The study also measured heart rate, blood pressure, and mood. Unlike many other thermogenic ingredients, Slendacor caused no stimulant effects: at no point during the study did heart rate or blood pressure significantly increase in the Slendacor group making it a non-stimulant thermogenic solution.

According to Jennifer Murphy, Director of Innovation & Clinical Development for PLT, the research offers insight into its effects on energy metabolism. “Our new data shows that Slendacor is not just limiting the formation of new fat cells, but also increasing the metabolic activity of existing fat cells. The browning of white adipose tissue means that those cells are now burning energy that may otherwise have been stored as fat,” she said. “Healthy weight management has long focused on reducing intake, however we know that metabolism is an equally important part of the equation for healthy and sustainable changes in body weight. These new data help us understand Slendacor as an integral part of a holistic health management program, providing support for both healthy body weight, as well as improved overall cardiometabolic health, opening up a range of new applications and use occasions for the Slendacor ingredient,” she added.

 Learn more about these studies. 



1. Dixit K, Kamath DV, Alluri KV, Davis BA. Efficacy of a novel herbal formulation for weight loss demonstrated in a 16-week randomized, double-blind, placebo-controlled clinical trial with healthy overweight adults. Diabetes Obes Metab. 2018 Nov;20(11):2633-2641

2. Choi HJ, Kim HY, Park KS. Antiobesity Effect of a Novel Herbal Formulation LI85008F in High-Fat Diet-Induced Obese Mice. Evid Based Complement Alternat Med. 2021;2021:6612996. Published 2021 Feb 8. doi:10.1155/2021/6612996

3. Kundimi S, Kavungala KC, Sinha S, Tayi VNR, Kundurthi NR, Golakoti T, Davis B, Sengupta K. Combined extracts of Moringa oleifera, Murraya koeingii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats. Lipids Health Dis. 2020 Aug 28;19(1):198. doi: 10.1186/s12944-020-01376-7. PMID: 32859217; PMCID: PMC7455912.

4. Murphy J, Salter D. P31-041-23 A Blend of Curcuma longa, Moringa oleifera, and Murraya koenigii Extracts Elevates Resting Metabolic Rate Without Changes to Heart Rate or Blood Pressure, Current Developments in Nutrition. 2023;7:101606


Featured News

ceratiq® Phytoceramides Receives Regulatory Approval for Sale and Beauty Claim in South Korea

May 10, 2021
Award-Winning Beauty-From-Within Ingredient Gets Certificate of Functional Ingredient for Functional Health Foods from Ministry of Food and Drug Safety

Morristown, NJ 10 May 2021 —

PLT Health Solutions, Inc. announced that ceratiq® Phytoceramides has been approved for sale in the Republic of Korea. A multi-year effort involving scientific and regulatory collaboration between PLT Health Solutions, ingredient innovator The Robertet Group (Grasse, France) and Korean distributor NOVAREX Co Ltd (Cheongju, Chungbuk, Korea) was behind the ingredient approval. ceratiq is a ceramide-rich natural ingredient for dietary supplements and cosmetics.  It offers a range of benefits that are associated with youthful skin including improved overall skin health, reduced appearance of wrinkles, increased elasticity, suppleness and a more radiant appearance. In its Certificate of Functional Ingredient for Functional Health Foods, the claim associated with ceratiq is: “May help to maintain skin moisturizing”. The ingredient, which was named Ingredient of the Year in the Healthy Aging Category by Nutraingredients-USA in 2018, has previously been featured in leading beauty-from-within products in the USA and Europe.

According to Jay Martin, Managing Director, Global Sales at PLT Health Solutions, the approval is a significant step forward for Robertet and PLT in the effort to help consumers and product formulators connect with ceratiq’s unique science and benefits. “The South Korean – K-Beauty – market is one of the most demanding in the world and one of the most influential. As a beauty-from-within ingredient, ceratiq Phytoceramides is perfect for the proactive ‘skin first’ philosophy central to the market,” he said. “Getting approval for ceratiq in the South Korean market was a collaborative effort between the scientists and quality teams of PLT, Robertet and NOVAREX to meet the rigorous approval process. We’re proud of what we’ve accomplished and have great expectations for new brands to enter the market with this innovative ingredient,” he said.

Strong Clinical Support Builds Trust and Momentum

ceratiq Phytoceramides is a leading dietary supplement beauty ingredient demonstrating powerful benefits for wrinkle reduction and skin hydration.

Most recently, a double-blind, placebo-controlled study was designed to evaluate the efficacy of ceratiq on skin hydration and on reduction of wrinkle appearance (Boisnic, 2019). The subjects received either 350 mg of ceratiq or placebo for 12 weeks. In the ceratiq group, wrinkles were significantly and visibly reduced, from 8 weeks (p < 0.001), compared to the placebo. The wrinkle reduction was visible for 88% of women after 12 weeks. The results demonstrated that skin was better hydrated as early as just 4 weeks. The persistence of gains in hydration and wrinkle reduction were demonstrated for two additional months after supplementation had concluded. Compared to the placebo, ceratiq was shown to offer three times the improvement in wrinkle visibility, 2.75 times the improvement in facial hydration and five times the improvement of radiance.

According to Irene Lamour, Business Development Director at the Robertet Health & Beauty division of the Robertet Group, the recent successes of ceratiq in global markets further validates the company’s vision for a high-quality beauty-from-within ingredient. “When we set out to create ceratiq, we wanted to have a sustainably sourced, premium quality plant-based ingredient backed by a strong body of clinical science. We believed that a nutrition-based solution could be the “new cosmetics” and that it makes sense for consumers that nutrition impacts the skin health and beauty. The age demographic for a product containing ceratiq runs from millennials to seniors, which can mean a lifetime relationship with consumers,” she said.

For more information, visit:


  1. Boisnic S, Keophiphath M, Serandour AL, et al. Polar lipids from wheat extract oil improve skin damages induced by aging: Evidence from a randomized, placebo-controlled clinical trial in women and an ex vivo study on human skin explant. J Cosmet Dermatol. 2019;18(6):2027‐2036. doi:10.1111/jocd.12967


NOVAREX is one of the leading companies for health supplements in South Korea. Established in 1995 as a research-oriented company, it has been developing functional ingredients and producing a full-range of dietary supplements including tablets, capsules(soft and hard), powder and stick jellies.  Today, NOVAREX manufactures and markets over two thousand products and is strongly committed to quality control. To meet customer demand, it has obtained ISO-9001 certification from USA’s Global Food Safety Initiative and HALAL certificate from the Korea Muslim Federation (KMF). NOVAREX keeps helping its customers improve their quality of life through better nutrition and healthier living.

About Robertet

Robertet is the world’s leading source of natural, sustainable, and organic ingredients and the only fragrance, flavor and ingredient company fully integrated at each step of the creation process, from the source ingredient to the final fragrance and flavor.  Founded in 1850 in Grasse, France, Robertet continues to be privately owned and managed by the fourth generation of family members.  With a passion for and unparalleled understanding of naturals, together with boundless creativity and market insight, Robertet provides its customers with world-class innovation in scent and taste.

About PLT Health Solutions

Headquartered in Morristown, NJ, USA, PLT Health Solutions is a trusted discoverer, developer, and marketer of high-quality, scientifically-supported ingredients that enhance health and functionality. As a leading ingredients innovator, PLT’s global network of strategic partnerships provides unique access to impactful solutions. PLT Health Solutions is a purpose-driven company passionate about helping people live healthier, happier lives. By delivering an unsurpassed mix of expertise, resources, and service, PLT is committed to helping both its strategic partners and valued customers grow.

Featured News

PLT Health Solutions Granted New, Expanded License for Weight Management Ingredient from Health Canada

February 17, 2021

Morristown, NJ 17 February 2021 — PLT Health Solutions, Inc. announced that it has received a new, expanded license from the Natural and Non-Prescription Health Products Directorate (NNHPD) of Health Canada to market its ingredient Slendacor® Weight Management Complex to support healthy weight loss in Canada. A former Nutraingredients Ingredient of the Year Award (2017) winner, Slendacor has been featured in top-selling consumer weight management brands in the United States, Brazil, Australia, Asia and Europe. Slendacor’s patented approach to weight management works at multiple levels by inhibiting the accumulation of fat in fat cells (lipogenesis) and enhancing the body’s ability to break down fat (lipolysis). The result is an ingredient that has been clinically shown to significantly enhance weight loss and help re-shape the body.

In Canada, previously approved claims include:

  • Exerts complementary weight management benefits when combined with a reduced-calorie diet and regular physical activity
  • Clinically shown to assist in weight management when used with a program of reduced-calorie intake and regular physical activity
  • Helps to support/Complements weight management when combined/ integrated with a calorie-reduced diet and regular physical activity
  • Weight management support by helping to complement your goals, when combined with a calorie-reduced diet and regular exercise
  • Helps support weight management when combined with a reduced calorie diet and regular physical activity

The new NPN adds claims for Slendacor that include support of healthy cholesterol and triglycerides:

  • Helps lower blood triglycerides, total and LDL cholesterol
  • Helps support cardiovascular health by reducing total and LDL cholesterol
  • Helps to reduce blood triglycerides, total and LDL cholesterol levels
  • Could be a complement to a healthy lifestyle that incorporates a calorie-educed diet and regular physical activity for individuals involved in a weight management/maintenance program

According to Jeremy Appleton, ND, Director of Medical & Scientific Affairs at PLT Health Solutions, the granting of the new NHP license by Health Canada is a significant milestone for Slendacor, because it opens up new applications for this well-established, unique ingredient.  “Healthy weight management has never been solely about shedding pounds. As important as weight loss is to many consumers, they know that healthy and sustainable changes to body weight must involve supporting other related systems, like cardiovascular and metabolic health. These new approved claims mean that we all can better understand Slendacor as an integral part of a holistic health management program, one that includes body weight, but in the greater context of cardiometabolic health,” he said.

Slendacor Starts Fasts and Finishes Strong

Slendacor Weight Management Complex has been shown effective in double-blind clinical trials to date, in both obese and healthy overweight subjects, with statistically significant improvements beginning as early as two weeks and continuing through the end of the studies. Slendacor has been shown effective in both men and women.

For more information, visit

About PLT Health Solutions

Headquartered in Morristown, NJ, USA, PLT Health Solutions is a trusted discoverer, developer, and marketer of high-quality, scientifically-supported ingredients that enhance health and functionality. As a leading ingredients innovator, PLT’s global network of strategic partnerships provides unique access to impactful solutions. PLT Health Solutions is a purpose-driven company passionate about helping people live healthier, happier lives. By delivering an unsurpassed mix of expertise, resources, and service, PLT is committed to helping both its strategic partners and valued customers grow