AprèsFlex® 5-Day Joint Support
New Study Demonstrates Cartilage Preservation and Protection
Four double-blind clinical trials demonstrate that AprèsFlex rapidly improves joint comfort, stiffness, flexibility, and physical function, with long-lasting benefits that continue to accrue.
A revolutionary new clinical study shows that AprèsFlex can also help maintain healthy joint space and preserve cartilage thickness, while decreasing markers of cartilage breakdown and inflammation. That makes AprèsFlex the most comprehensive mobility solution on the market today. It will enable the development of products with benefits that will change people’s lives.
A Patented, Synergistic Extract of Boswellia serrata
AprèsFlex is a patented, synergistic combination of two proprietary extracts derived from Boswellia serrata gum resin. The oral bioavailability of acetyl-11-keto-beta-boswellic acid (AKBA) from AprèsFlex is significantly higher than that of other commercially available Boswellia extracts, which allows for a lower daily dose and enhanced efficacy. AprèsFlex is used often as a standalone ingredient or in conjunction with other ingredients to power some of the best-known joint health consumer brands in the world.
Flexibility is Freedom
When we play a round of golf or spend an afternoon on our knees in the garden or just take a nice long walk, we are celebrating our freedom.
AprèsFlex has been giving people back their freedom for almost a decade, by delivering joint comfort and flexibility from 100 mg dose that starts to work in only 5 days.
Around the world, people have turned to AprèsFlex more than a billion times as a drug-free approach to joint comfort. They trust the science. Trust the quality. And trust the experience.
One of the most clinically studied mobility support ingredients on the market
AprèsFlex 5-Day Joint Support has been the subject of extensive preclinical and clinical research to demonstrate its mechanisms of action and efficacy in supporting joint comfort and mobility.
In its third clinical study, AprèsFlex was found to:
- Provide significant reduction (p<0.05) in all pain scores at five days compared to the placebo*
- Provide significant improvement (p<0.05) in all function scores at five days compared to placebo*
Visual Analog Score (VAS) (Graph A)
Lequesne Index (LFI) (Graph B)
WOMAC Index ((Graphs C, D, E)
In its fourth clinical trial, at six months AprèsFlex was found to:
- Improve joint comfort by 70%*
- Reduce stiffness by 72%*
- Enhance physical function*
- Improve walking speed by 27%*
Cartilage Preservation and Protection
In its fourth clinical trial, AprèsFlex was found to:
- Mitigate loss of joint space compared to placebo*
- Preserve cartilage thickness*
- Reduce markers of cartilage breakdown*
(^p<0.05 vs placebo)
For more information on AprèsFlex science, see the Resources section below.
A Sustainable and Socially-Responsible Ingredient
When your customers purchase a product featuring AprèsFlex, they become part of a story that is both sustainable and socially responsible. AprèsFlex is a proprietary Boswellia serrata gum resin extract. Over the last 25 years, PLT has worked with our innovation partner – Laila Nutraceuticals – to create an environment that can assure not only the highest quality ingredient with proven efficacy, but an ingredient that you and your customers can be proud of.
PLT Boswellia serrata materials are sourced in India from the states of Andhra Pradesh and Madhya Pradesh. The entire Boswellia serrata supply chain starts with deep, long-term relationships developed with the most trustworthy collectors and aggregators that have been decades in the making. In conjunction with the Indian forestry department, collectors are trained on sustainable gum tapping methodology to maximize yield while maintaining the safety and health of the Boswellia serrata tree populations. Tapping locations on the tree bark as well as the frequency of tapping are carefully controlled to maintain good tree health.
In early 2022, PLT Health Solutions announced the commencement of a third-party sustainability audit program on Boswellia serrata trees in India by renowned botanical research consultancy Botanical Liaisons, LLC. The third-party audit program is based on a broad range of environmental, cultural and economic parameters.
At PLT, we understand that proper stewardship of natural resources and social responsibility toward the communities that support our work is both the right thing to do and good business.
PLT Mobility Solutions
At PLT, we are working on the concept of Mobility Solutions – that include benefits for joints, muscle and cartilage. We’re thinking about athletes who want to perform better and recover faster. We’re thinking about people who have physically demanding jobs who don’t want to or can’t take a day off from work. We’re thinking about anyone who has an active lifestyle who wants to embrace it despite the rigors. And yes, we’re thinking about the global aging population.
PLT Health Solutions’ leading portfolio of mobility support ingredients – based on more than a decade of ongoing research – has been developed to help you deliver innovative products that can capture the attention and the trust of consumers. All our ingredients are backed by multiple clinical studies – and offer rapid improvements from a low dose – in just about any delivery system you can imagine.