ceratiq® for Animal Health
Phytoceramides are the key
ceratiq® Phytoceramides is an ingredient rich in plant lipids, with human clinical studies that suggest beneficial ap[plications in animal supplements. Its major components are phytoceramides, glycolipids, and phospholipids. Rich in digalactosyl diglyceride (DGDG), a key glycolipid in cellular membranes, ceratiq is truly innovative in its composition and activity.
ceratiq has been shown in preclinical and human clinical research to improve skin hydration and reduce signs of dry skin, such as flaking, itching, and redness.* Ceramides are integral to skin cell membranes, comprising 35-40% of intercellular cement, the part of the connective tissue that binds together keratinocytes, other cells, and structural elements of the epidermis.
These essential lipid components of the stratum corneum—the outermost layer of the epidermis—are often deficient in inflammatory skin conditions. Phytoceramide supplementation is a safe and effective way to replenish these vital skin lipids.
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A history of traditional use validated by scientific study
A skin barrier study in dogs documented increased trans-epidermal water loss in the inguinal skin of dogs compared with healthy controls. Protecting the skin barrier of companion animals appears to be especially important, especially for those experiencing inflammation.
Research in humans has shown that function of the lipid barrier of the stratum corneum is impaired in common skin conditions. Studies also document a deficiency of ceramides in the stratum corneum in these groups. Ceramides are the most abundant type of lipid found in this layer of the epidermis.
A randomized controlled clinical trial in humans evaluated the efficacy of ceratiq on skin hydration and on overall wrinkle reduction. Subjects received either 350 mg of ceratiq oil or placebo daily for 12 weeks, with 8 weeks of follow-up. Skin hydration was significantly increased in subjects taking ceratiq compared to those taking placebo. Skin roughness and radiance were also significantly improved in the ceratiq group compared to placebo group. And in an adjunct study, a higher collagen content was measured in UV-irradiated skin explants treated with ceratiq compared to the untreated ones.