menatto® Vitamin K2
Bone and Heart Health for People of All Ages
MK-7 from PLT is menaquinone-7, a form of Vitamin K2. PLT MK-7 There are two broad categories of Vitamin K used in supplements. Vitamin K1 (phylloquinone or phytonadione) is the form found in plants, such as leafy green vegetables. Vitamin K2 (menaquinone, such as MK-4, and MK-7) is found in animal and certain fermented foods. Menaquinones naturally have greater bioavailability. At least 50-60% of the circulating Vitamin K in the body is in the form of K2. The MK-7 form of vitamin K2 is the most bioavailable form of Vitamin K. This was established by research done specifically on J-Oil Mills’ MK-7. Human clinical trials with menatto have demonstrated higher bioavailability than MK-4, and more than seven times the bioavailability of vitamin K1, making menatto the most bioavailable vitamin K commercially available. Another study demonstrated that menatto is bioavailable in diverse delivery systems.
menatto Vitamin K2 has been the subject of ten human clinical studies on the actual article of commerce – more than any other Vitamin K2 on the market.
Post-Menopausal Women and Bone Health
A 3-year, randomized, double-blind, placebo-controlled study of post-menopausal women found that supplementing with low-dose menatto Vitamin K2 helped bind calcium to bones, supporting healthy bone mineral density.* menatto significantly improved vitamin K status compared to placebo and helped support bone mineral density (BMD) and bone strength.*
Knapen MHJ, et al. Osteoporos Int. 2013 Sep;24(9):2499-507.
Bone Health for Middle Aged Men and Women:
Ninety-four participants with an average age of 52.4 were randomly assigned to take either 180 mcg of menatto per day or placebo for 1 year. They were advised to take two other nutrients — vitamin D and calcium since this trio works together to support bone health.* Researchers followed up at 2, 6, and 12 months and took measurements of bone mineral density at the lumbar spine and the femoral neck. menatto supported bone mineral density in thelumbar spine and supported bone mineral content in the femoral neck, which is an indicator of bone strength.*
Forli L, et al. Transplantation. 2010 Feb 27;89(4):458-64.
Calcium Metabolism in Children:
A randomized, double-blind, placebo-controlled study of pre-pubescent children found that menatto vitamin K2 effectively raised blood levels of vitamin K2 compared to placebo, and helped ensure the proper level of carboxylated osteocalcin, a protein that regulates healthy bone formation.*
van Summeren MJH, et al. Br J Nutr. 2009 Oct;102(8):1171-78.
Supporting Health blood vessel elasticity
A 3-year, randomized, double-blind, placebo-controlled study of healthy post-menopausal women found that three years of supplementation with menatto supported healthy blood vessel elasticity by helping maintain the right type of matrix Gla protein in the blood vessel wall.* This action may support healthy blood flow, contributing to cardiovascular health.*
Knapen MHJ, et al. Thromb Haemost. 2015 May;113(5):1135-44.
For more information on how Earthlight and MK-7 from PLT can work together, contact us.
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