

Supresa™ Crave Control

Scientifically shown to help fight snacking
Keto? Paleo? Mediterranean? Low fat? No matter what your program is, why not add Supresa™ to your product and give your customers the willpower they’ll need to help them succeed. Supresa induces a feeling of well-being and stress reduction to address the source of stress-related overeating and snacking. The best news? Clinical studies suggest that it starts working before 14 days. Supresa represents a different mechanism of action for weight management – giving you an opportunity to differentiate your product.
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Clinically-studied
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Patented
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Fast-acting
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Kosher, Halal, non-GMO
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Natural, clean label
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Exciting consumer messaging
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Safe, side-effect free
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Water-soluble
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GRAS

Weight Management
When trying to lose weight, who couldn’t use a little help in staying away from snacking? The best news? Supresa can be used in a wide range of ‘fun’ foods and beverages including lollipops, gums, chews and shakes because of a low dose, minimal organoleptic impact and excellent solubility.


Active/Sports Nutrition
For body builders and physique trainers, Supresa can help them regulate when and where they’ll eat before competition.
Research that builds trust with consumers
No matter what your program is, why not add Supresa to your product and give your customers the state-of-mind they’ll need to help them succeed. Supresa induces a feeling of well-being and stress reduction to address the source of stress-related overeating and snacking – a different mechanism of action for weight management from other weight management ingredients.
In a study conducted with 60 healthy, only slightly overweight women (BMI 25-30) who were between 25-45 years old, Supresa intake over t8 weeks resulted in significantly greater body weight reduction than the placebo group. Supresa decreased snacking by 55% compared to a 28% reduction by the placebo group. The decrease in appetite was 69% in the Supresa group versus 54% in the placebo group. There were no reports of side effects in the study groups, and compliance with the Supresa regimen was excellent.
SUPRESA AIDS IN WEIGHT MANAGEMENT
A double-blind placebo-controlled study shows that Supresa may decrease hunger, reduce sugar cravings and reduce snacking between meals. Clinical studies have shown that women taking Supresa report decreased hunger. Weight loss has also been demonstrated.

GLOBAL INTELLECTUAL PROPERTY
Supresa is the only saffron-based weight loss ingredient with patent protection in global markets. The patents cover the use of saffron, the saffron extracts crocin and picrocrocin, and derivatives of these, as an ingredient in support of a healthy weight.
Global Patents Issued: US 9,833,489 B2 Canada: 2648985 Europe: 2,010,012 Japan: 6,093,425
What is Supresa Crave Control?
Supresa is an extract of Crocus sativus L. saffron stigmas, is rich in safranal, crocin and picrocin. This proprietary extract is standardized to >0.3% safranal. Supresa was developed to support weight management, by improving emotional wellbeing and decreasing snacking behavior. Unlike other products, SUPRESA does not act acutely to promote a feeling of ‘fullness.’ Rather, it induces a feeling of wellbeing and stress reduction over time to address the source of stress-related overeating and snacking. This ingredient is the only saffron extractable to promote weight management benefits through both patent protection and clinical support.
How Does Supresa Work?
Many ingredients designed to inhibit the desire to snack act on physiological or hormonal factors. Supresa’s clinically studied formula improves levels of the neurotransmitter serotonin. The proposed mechanism of action through which Supresa is thought to exert efficacy is by serotonin reuptake inhibition (Perovic, 1995 unpublished data), whereby a sense of wellbeing is achieved. Serotonin is a neurotransmitter that influences satiety, appetite, mood, compulsiveness and anxiety. It is notable that Supresa consistently shows greater than 50% inhibition of serotonin reuptake from lot-to-lot testing, whereas the same results were not obtained from generic saffron extracts (unpublished data on file).
MODES OF WEIGHT LOSS
- Highly conserved by redundant mechanisms
- Regulated by many pathways
- Effective weight management should target multiple mechanisms

Supresa can be used…. everywhere.
If you are talking about a weight loss supplement, Supresa can be added as an ingredient to improve the performance of that supplement – adding the dimension of crave control – or what we are calling ‘power against snacking’ – to the formula. The same holds true for diets and meal plans.
Ideal applications for Supresa as an ingredient in the food space include confectionary – in candies, gums and chews, bars of all kinds including protein bars, a range of snacks and meal replacements. In the beverage space, Supresa has been explored in coffee and tea drinks, milk beverages, fruit beverages and shakes – as well as ‘shots’
Adding Supresa will not change the taste or appearance of products. From a formulating standpoint can be mixed with vitamins, minerals, starches, flavors, aromas, sweeteners for easy incorporation.
Find out more about the PLT Weight Management portfolio.
Supresa Crave Control is part of our growing portfolio of scientifically-supported weight management ingredients. Why not find out what we can do for you?